Up to 40% OFF Spring Offers >>>

N-Acetyl Glucosamine: How To Reduce Age Spots and Hyperpigmentation

What is N-Acetyl Glucosamine?

Known for its various health and skin benefits, N-Acetyl Glucosamine is a nano peptide naturally extracted from the outer shells of shellfish. Peptide is part of the protein structure that gives your skin strength and elasticity. 

N-Acetyl Glucosamine Boosts The Skin's Hyaluronic Acid Production

Due to its nano particle size, N-Acetyl Glucosamine can penetrate deeper into the skin. It boosts the skin's hyaluronic acid synthesis and reduces inflammation. N-Acetyl Glucosamine is the basic component of hyaluronic acid, a major skin component that plays an important role in the youthfulness of your skin. It plumps up the appearance of your skin.

Just like with other skin components, the levels of hyaluronic acid in the skin decline with age, triggering the appearance of wrinkles, lines and other signs of ageing. Many studies showed that N-Acetyl Glucosamine helps reduce and reverse signs of ageing including age spots, hyperpigmentation, wrinkles, dryness and loss of skin volume.

N-Acetyl Glucosamine Reduces Facial Hyperpigmentation and Brightens Complexion

Add more years to your appearance than wrinkles, age spots are the signs of accumulated skin damage over a period of time due to excessive exposure to UV radiation or hormonal changes during pregnancy and menopause.

Studies showed that N-Acetyl Glucosamine reduces facial hyperpigmentation by inhibiting the melanin production and protecting skin cells from free radicals and oxidative stress. The skin brightening effects of N-Acetyl Glucosamine is further boosted when it is mixed with Niacinamide (vitamin B3) in a skincare formula.

The skin renewal, smoothing and brightening properties of N-Acetyl Glucosamine are similar to those of Alpha Hydroxy Acids. Even better, N-Acetyl Glucosamine is suitable for all skin types including hyper-sensitive skin.


“Excellent serum to use for the night to achieve great complexion, very effective!" Jasmine T.

Is N-Acetyl Glucosamine a Safe Skin Whitening Ingredient?

Skin Whitening Products are very popular in many countries, particularly in Asia and Africa. As an anti-ageing scientist, I formulate skincare products to help preserve the youthfulness of the skin. I believe that healthy skin is the key to youthful-looking skin. Many whitening skincare products have been formulated with hydroquinone and kojic acid that may have adverse effects on skin health. I strongly recommend to read the ingredient list before you buy any skincare product. Hydroquinone has been banned in Europe for over the counter skincare or cosmetic products. However, some over the counter skincare products from USA and many other countries still contain hydroquinone.

The two ingredients that I use to reduce age spots and hyperpigmentation, N-Acetyl Glucosamine and Niacinamide, have been proven to be safe and help slow down skin ageing. The way these ingredients brighten the appearance of the skin is by preventing the excess melanin production and boosting skin cell renewal. 

N-Acetyl Glucosamine Reduces Wrinkles and Other Signs of Ageing

Numerous studies showed that N-Acetyl Glucosamine improves the appearance of ageing skin. It reduces wrinkles, lines, age spots, loss of skin volume (sagging skin), dryness and dehydration. The anti-ageing effects of N-Acetyl Glucosamine are due to its ability to boost hyaluronic acid synthesis, strengthen skin matrix and improve skin cell turnover. N-Acetyl Glucosamine slows down the signs of ageing and restores the youthfulness of the skin. It helps unclog pores and gently peels off dead skin cells that makes it suitable for acne-prone skin too.

N-Acetyl Glucosamine in Anti-Ageing Skincare Products

Due to its excellent stability, skin penetrating and rejuvenating properties, N-Acetyl Glucosamine is one of the best anti-ageing ingredients for skincare products. I don't believe there is anything to stop the ageing process completely, nevertheless, I do believe that anti-ageing skincare products can slow down the signs of ageing. I use a combination of n-acetyl glucosamine, niacinamide, stabilised vitamin E, hyaluronic acid and botanical extracts in my award-winning anti-ageing moisturiser, Bio-Collagen Ageless Cream.

Testimonial: "When a girl reaches certain age a little smudge of Henry's magic goes a long way! It slides onto skin as smoothly as silk and leaves your face feeling plumped-up. What's more, for really exciting effects, introduce Henry to other parts of your body; you'll be amazed with the wrinkle-free results!" Best Night Cream, Natural Health (Beauty Awards Panel), UK.



Brightening Skincare Routine

In adults, skin renews itself every 28 to 42 days. A healthy skin renewal is the key to reduce the appearance of age spots and hyperpigmentation. Henry Tianus Skin Brightening Anti-Ageing Collection has been specially developed to speed up skin cell renewal and reduce the appearance of age spots, hyperpigmentation and other signs of ageing.

How to use Henry Tianus Skin Brightening Anti-Ageing Collection?

In the morning, apply Bio-Collagen Ageless Cream to all over the face and neck, particularly to those areas affected by age spots and hyperpigmentation. This extra firming and lifting cream can be used after your usual serum and before sunblock.

At night, apply Overnight Skin Perfector on freshly-cleansed skin, avoiding the immediate eye area. Follow with the application of Bio-Collagen Ageless Cream. Overnight Skin Perfector has been formulated with liquorice extract, alpha and beta hydroxy acids to boost skin renewal at night and even out skin tone.

Henry Tianus Skin Brightening Anti-Ageing Collection is suitable for all skin types and during pregnancy and menopause.


" Because I care greatly about the health and beauty needs of my patients, I chose Henry Tianus for its high efficacy in delivering brilliant results." dr. Dylan Chau.


Henry Tianus is a multi-award-winning Anti-Ageing Scientist based in London, UK. Henry Tianus has been listed as The Recognised Institute Practitioner at The Institute of Traditional Herbal Medicine and Aromatherapy (ITHMA), London (UK) since 2005. Henry Tianus's articles have been read by people in more than 100 countries with USA, UK and Singapore at the top of the list. Join Henry Tianus eNewsletter to receive the latest health and wellbeing tips. 

 Click To Join Henry Tianus eNewsletter >>>  


You may also like:


Coronavirus Outbreak: Plasma Therapy To Cure Covid-19

The recovery rate from coronavirus infection in China rose to 46%. 36,445 Covid-19 patients in China have recovered; while outside China, the recovery rate in 57 countries all together is about 8%. China has developed plasma therapy that improves the condition of critically ill Covid-19 patients within 12 to 24 hours.

 Read More >>> 



Resveratrol Reduces Hot Flashes, Risk of Cancer and Skin Ageing

Menopause doesn't increase the risk for cancer. Studies suggest that the long exposure to estrogen prior to menopause increases the risk of various cancers. Women who experienced menopause after the age of 55 or began menstruating before the age of 12 are both at a higher risk of having ovarian, breast and uterine cancer.

 Read More >>> 



How Long does it take for Your Skin to Renew?

The skin cells turnover rate varies individually and age plays a major role. In babies, the skin renews itself every 14 days. For teenagers, this process takes about 28 days. In adults, it takes between 28 and 42 days. While for those age 50 and older, it may take up to 84 days.

 Read More >>> 



The Health Benefits of Eating Garlic

Garlic has been shown to lower blood pressure, reduce LDL cholesterol levels and prevent the hardening of the arteries. Studies suggest that eating garlic helps decrease the risk for heart disease, diabetes, cancer and many other diseases. Garlic protects the liver from toxic chemicals and boost the body's immune system.

 Read More >>> 



Why Colloidal Gold Skincare is Great for Your Skin

Colloidal Gold is a suspension of gold nanoparticles in a fluid, usually water. Known for its antioxidant and anti-inflammatory properties, studies showed that colloidal gold can penetrate deeper into the skin and acts as a carrier for other active ingredients to improve the efficacy of the skincare products.

 Read More >>> 



Why Curcumin In Turmeric Is Greatly Beneficial for Your Health

Studies showed that curcumin has excellent anti-inflammatory properties, comparable to those of anti-inflammatory drugs. Even better, unlike those drugs, curcumin doesn't have the toxic effects. Due to the curcumin content, turmeric helps reduce inflammation in people with rheumatoid arthritis, diabetes, psoriasis, eczema and heart disease.

 Read More >>> 



How Digital Devices May Affect Our Health and Wellbeing

A research study by Harvard Medical School showed that the exposure to blue light emitted from digital screens and lights at night suppresses the melatonin secretion in our body. Melatonin is the hormone which regulates the body clock. This hormone is very crucial to our health and wellbeing. Melatonin helps us to fall asleep at night.

 Read More >>> 



Scientific Sources: Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine, Journal of Cosmetic Dermatology, 2007 Mar, 6(1): 20-6; The effect of N-acetyl-glucosamine on stratum corneum desquamation and water content in human skin, Journal of Cosmetic Science, 2009 Jul-Aug, 60(4): 423-8; Topical n-acetylglucosamine provides fast acne-reducing benefits and mildness demonstrating its potential utility in enhancing conventional Rx or OTC acne treatments, Journal of the American Academy of Dermatology, February 2007, Volume 56, Issue 2, Supplement 2, Page AB19; Oral N-acetylglucosamine supplementation improves skin conditions of female volunteers: Clinical evaluation by a microscopie three-dimensional skin surface analyzer, Journal of Applied Cosmetology 20, 143-152, April/June 2002; A Firming Neck Cream Containing N-Acetyl Glucosamine Significantly Improves Signs of Aging on the Challenging Neck and Décolletage, Joel Schlessinger, MD1 and Barbara Green, RPh, MS2 and Brenda L. Edison, BA2 and Lynn Murphy, MA2 and Yamini Sabherwal, PhD; Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytes, Osteoarthritis and Cartilage, 2009 Aug, 17(8): 1022–1028; N-acetylglucosamine reduces inflammatory response during acute peritonitis in uremic rats, Blood Purification, 2006, 24(3): 274-81; Genomic expression changes induced by topical N-acetyl glucosamine in skin equivalent cultures in vitro, Journal of Cosmetic Dermatology, 2007 Dec, 6(4): 232-8; Cosmeceuticals for Hyperpigmentation: What is Available?, Journal of Cutaneous and Aesthetic Surgery, 2013 Jan-Mar, 6(1): 4–11.

Leave a comment