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Niacinamide (Nicotinamide) for Youthful Radiant Skin

What is Niacinamide?

Niacinamide is an essential water-soluble vitamin in human diet. Known as vitamin B3, it was first recognised as vitamin PP in the early 20th century due to its capability in preventing pellagra, an epidemic disease with severe cutaneous lesions. The other name for Niacinamide is Nicotinamide. 

The Cosmetic and Skincare Uses of Niacinamide

The development of Niacinamide as a topical skincare ingredient was pioneered by two scientists, Feldmann RJ and Maibach HI who highlighted the good skin penetration of Niacinamide. Unlike Niacin, another form of Vitamin B3; Niacinamide does not cause flushing or skin irritation. It has excellent soothing properties; therefore, it is suitable for all skin types including very sensitive skin. 


Henry Tianus on Niacinamide

The Skin Benefits of Niacinamide

1. Niacinamide hydrates and strengthens skin barrier function

A-4-week clinical studies showed that Niacinamide reduced transepidermal water loss in stratum corneum (the outermost layer of the skin) by 24%. At the same time, Niacinamide increased the amount of free fatty acids and ceramides in stratum corneum by 67% and 34%.

2. Niacinamide increases skin's collagen production and reduces overall signs of ageing

Niacinamide increases the production of collagen in the skin by up to 54%; while it also increases the production of elastin and skin proteins by up to 20% and 100%. A clinical study showed that Niacinamide significantly improved the appearance of ageing skin. The skin's elasticity and firmness were improved. The appearance of fine lines, wrinkles, dark spots, red blotchiness and skin sallowness (yellowing) were visibly reduced. 

3. Niacinamide improves the appearance of acne-prone skin

Niacinamide has anti-inflammatory properties that are beneficial to those with inflammatory skin conditions such as acne vulgaris. A clinical study showed that topical application of Niacinamide reduced the acne inflammation by 52%, without the drying effect to the skin.


4. Niacinamide soothes sensitive and rosacea-prone skin

A 4 weeks study involving 50 rosacea sufferers showed that Niacinamide improved the overall skin condition and eased the symptoms of rosacea.

5. Niacinamide helps protect skin against UV-induced damage

A study by University of Sydney at Royal Prince Alfred Hospital, Australia showed that Niacinamide blocked different types of ultraviolet light. It helps reduce UV-induced skin damage and decreases the risk of skin cancer.

6. Niacinamide brightens complexion and lightens dark spots

Niacinamide doesn't reduce the production of melanin, however, it helps prevent Melanin to reach the top layers of the skin by up to 68%. In a-8-week clinical-trial, Niacinamide has been shown to reduce the appearance of dark spots by more than 25%. Age spots around the eye and cheek were visibly reduced.

A clinical study showed that the efficacy of Niacinamide in diminishing dark spots is further boosted by teaming it up with N-Acetyl Glucosamine. These synergistic radiance-boosting ingredients are two of the ten bioactives in Bio-Collagen Ageless Cream. This haute couture regenerating cream helps reduce the signs of ageing such as wrinkles, lines, sagging skin, uneven skin tone and age spots.


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Scientific Sources: 

The British Journal of Dermatology, 2010 Feb 1;162(2), Pages 435-441: "Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial."

Dermatologic Surgery, 2005 Jul, 31 (7 Pt 2), Pages 860-865: "Niacinamide: a B vitamin that improves aging facial skin appearance." 

International Journal of Cosmetic Science, 2004 Oct, 26(5), Pages 231-238: "Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin."

The British Journal of Dermatology, 2002 Jul, 147(1), Pages 20-31: "The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer." 


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