Free Delivery Worldwide >>>

How Dihydrotestosterone Causes Hair Loss (Androgenetic Alopecia)?

What is Dihydrotestosterone?

Dihydrotestosterone, also known as DHT, is a powerful sex hormone, stronger than testosterone, the most commonly known androgen hormone.

 

How Dihydrotestosterone Get Created in The Body?

Our body creates dihydrotestosterone with the help of 5α-reductase, the enzyme found in the reproductive organs (testes, ovaries), prostate, skin, hair follicles and other internal organs. 

5α-reductase plays an important role in steroid metabolism in the body, it converts testosterone to dihydrotestosterone. In general, about 10% testosterone in the body gets converted into DHT. Dihydrotestosterone is the hormone behind the male characteristics such as body and facial hair, deep voice and muscles.

Do Women Have Dihydrotestosterone in Their Body?

Although women have much lower testosterone levels than men, women produce testosterone in their body too. Due to the presence of 5α-reductase, some of the testosterone gets converted into dihydrotestosterone. High dihydrotestosterone levels in women have been associated with the excess facial and body hair, irregular menstrual periods and persistent acne.

 

How Dihydrotestosterone Affects Hair on The Scalp?

For some people, the presence of dihydrotestosterone in the hair follicles doesn't affect the hair life cycle, however, for some others, it triggers the thinning of the hair. In certain cases, DHT causes baldness in both men and women.

There have been countless studies on hair loss, however, it is yet to be fully understood why dihydrotestosterone causes hair loss in some individuals. Is this kind of an autoimmune disease?

Dihydrotestosterone Attacks Hair Follicles

Dihydrotestosterone may cause hair follicles to shrink gradually. Over the times, hair appears visibly weaker, shorter and thinner.  In science, the term of androgenetic alopecia is used for a hair loss condition caused by androgen hormones, particularly dihydrotestosterone. Left untreated, this hair loss condition may cause baldness in both men (male pattern baldness) and women (female pattern baldness).

 

 

How exactly DHT causes hair follicles to shrink is not yet fully understood, however, the mechanism of DHT action in androgenetic alopecia can be explained in two steps:

1. Dihydrotestosterone Shortens The Anagen Stage of The Hair

For people who don't suffer from hair loss, during the anagen stage, their hair keeps growing for a period of three to five years. However, for those who suffer from androgenetic hair loss, their hair follicles are sensitive to DHT. Dihydrotestosterone causes their hair follicles to shrink. As a result, the hair can't no longer grow as long as it would be. The hair becomes gradually thinner and shorter. In men, the temple and crown are the first two most common areas affected by hair loss.

2. Dihydrotestosterone Lengthens The Telogen Stage of The Hair

In addition to shortening the Anagen stage, DHT lengthens the resting stage of the hair. At advanced stages of hair loss, hair follicles are no longer alive. When the hair follicles are already dead, there is nothing can be done to bring them back to life. Even with hair transplantation where hair follicles from the donor site are transplanted to the balding area, it is not possible to fully restored the hair density.

As hair loss is usually a gradual process over a period of time, a proper treatment at early stages of hair loss can significantly slow down the progress and prevent baldness. In the next article, Hair Loss and Thinning Hair Treatment, you can learn how to reduce hair loss and stimulate hair growth.

Testimonial: FANTASTIC! Dear Henry, today my hair loss patient who started using Henry Tianus Hair Loss Solution Products one week ago, came to my clinic and told me that Henry Tianus products are FANTASTIC. His hair look healthier and stronger already. Congratulation Henry, good job. " dr. Agustin Blanch, Spain.

 

Author:

Henry Tianus is a multi-award-winning Anti-Ageing Scientist based in London, UK. Read >>>

 

 

Related Article:

Hair Loss and Thinning Hair Treatment. Read >>>

You may also like:

Rose Gold Antioxidant Youthful Serum with 24-karat nano gold, rose extract, allantoin, pro-vitamin B5, saccharide isomerate, prickly pear and cacay oil to help prevent premature skin ageing and reduce the existing signs of ageing.

Bio-Renewal Face Oil, a rejuvenating radiance oil with blue chamomile, frankincense, coenzyme Q10, cacay and rosehip oil to boost skin radiance, even out complexion and minimise the appearance of wrinkles, fine lines and age spots.

Nano Gold Nourishing Cream with 24-karat colloidal gold, saccharide isomerate, blue chamomile, frankincense, shea butter, rosehip and rice bran oil to prevent skin dryness and minimise the appearance of wrinkles and fine lines.

Ultra Smoothing Cellulite Serum Oil with vitamin E, menthol, palmarosa, grapefruit, lemon, rosemary, black pepper and sweet fennel essential oils to firm and smooth the appearance of orange-peel skin.

Bio-Collagen Serum, an award-winning rejuvenating lifting serum with ultra-low-molecular-weight hyaluronic acid, coenzyme Q10, ferulic acid, resveratrol, vitamin E, nano gold particles, rose and scutellaria extract.

 

 

Melt Away, a Triple Action Facial Cleanser that can also be used as a makeup remover, deep-cleansing mask and gentle exfoliator.

Hair Growth Serum, a scalp revitaliser for thinning hair with caffeine, niacinamide, menthol, rosemary, thyme, ylang ylang and cedarwood essential oils to reduce hair loss and stimulate hair growth.

Ultra Nourishing Repair Balm for Stretch Marks and Dry Skin with vitamin E, Rosewood, Neroli, Prickly Pear, Pomegranate, Sea Buckthorn, Chia Seed and Evening Primrose oil to reduce the appearance of stretch marks, dry patches and signs of ageing. Perfect for dry lips, hands and feet too.

Bio-Collagen Skincare Collection, the Ultimate Anti-Ageing Skincare Collection to rejuvenate your skin and slow down the signs of ageing. Highly recommended for those in their 40s, 50s, 60s and beyond or for younger people who suffer from premature skin ageing.

Hair Loss Solution for Men and Women, a set of thinning hair treatment products to rejuvenate hair follicles and stimulates hair growth.

 

 

Antioxidant Youthful Essence, a multi-award-winning Anti-Pollution Hydrating Mist with allantoin, panthenol, turmeric, ginkgo and blue chamomile essential oil to protect skin from free radicals and pollutants.

Gentle Eye Cream with caffeine and rosehip oil to reduce signs of ageing and get rid of puffy eyes and dark circles.

Flower Essence Hydra-Calming Toner with a synergistic blend of nine flower extracts to gently awaken the sense and instantly freshen tired skin.

Bio-Collagen Ageless Cream, an extra firming and lifting cream with ultra-low-molecular-weight hyaluronic acid, niacinamide, n-acetyl glucosamine, coenzyme Q10, argan oil, shea butter, 24-karat gold nanoparticles, vitamin E, gotu kola and rose extract.

Scalp Stimulator, a pre-shampoo hair root activator for thinning hair with cannabis sativa, rice bran, menthol, vitamin E, rosemary, cedarwood, thyme, ylang ylang and lemon essential oils to revitalise hair follicles and boost hair growth.

 

 

Overnight Skin Perfector, an advanced complexion repair serum with blue chamomile, liquorice root, panthenol, alpha and beta hydroxy acids to boost cell renewal, even out skin tone and diminish the look of wrinkles and lines.

Rose and Cacay Hydrating Cream, the award-winning antioxidant hydrating moisturiser with rose extract, cacay oil and saccharide isomerate to boost skin's hydration levels, plump up and reduce the appearance of wrinkles and lines.

Hydra Calm, a two-in-one Ultra Comforting Cleansing Cream and Soothing Mask to remove all traces of dirt including makeup, or alternatively to hydrate and comfort sensitive skin.

Blemish Clearing Serum, a 2% Salicylic Acid Solution to unclog congested pores, regulate sebum production and renew the appearance of blemished skin.

Chamomile & Cacay Oil, a 100% natural botanical formula with blue chamomile, rice bran and cacay oil to lock in moisture, strengthen skin's natural defense, soothe and revitalise undernourished sensitive skin.

 


 

Scientific Sources: Serum Levels of Androgen-Associated Hormones Are Correlated with Curative Effect in Androgenic Alopecia in Young Men, Medical Science Monitor, 2018, 24: 7770–7777; Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia, Advances in Dermatology and Allergology/Postępy Dermatologii I Alergologii, 2014 Aug; 31(4): 207–215.